Adult Dosing

Preoperative skin preparation

• Apply single uniform coat of solution to clean, dry, residue-free, intact skin at the incision line towards the periphery

• Do not scrub and reprep area
• Allow skin to dry (3 minutes on hairless skin; up to 1 hour in hair) until it turns shiny to dull in appearance

Pediatric Dosing

• Safety and effectivness in pediatric patients have not been established

[Outline]

• Adult Dosing
• Pediatric Dosing

• Preoperative skin preparation and reduce bacteria that may cause skin infection

• Hypersensitivity to any of the ingredients of the product
• Open wounds, mucous membranes, or as a general skin cleanser
• Infants <2 months old

• N/A

Renal Dose Adjustment

• Renal impairment: No dose adjustments

Hepatic Dose Adjustment

• Hepatic impairment: No dose adjustments

• Keep solution away from fire or flame. For external use only
• Caution should be exercised in infants <2 months old due to the risk of excessive skin irritation and transient hypothyroidism
• Avoid contact with eyes, ears, mouth and mucus membranes as this solution may cause serious injury if permitted to enter and remain; rinse with cold water and consult doctor if contact occurs
• Discontinue use if irritation, sensitization or allergic reaction occurs
• If swallowed accidentally, seek medical attention or contact a Poison Control Center immediately

Pregnancy Category:NR

Breastfeeding: Safety unknown. Manufacturer advises caution

• HYPERSENSITIVITY: Irritation, sensitization, allergic reaction

• Antiseptic; has broad spectrum bactericidal activity against gram-positive and gram-negative bacteria and also fungicidal, protozoacidal, cysticidal, virucidal, and some sporicidal activity
• Minimal systemic absorption
• Metabolism: Unknown
• Renally excreted
• Half-life: Unknown

Isopropyl alcohol

• Disinfectant; it acts as local anti-infective agent
• Metabolism: Unknown
• Excretion: Unknown
• Half-life: Unknown

US Trade Name(s)

• Duraprep

US Availability

Duraprep (iodine povacrylex/isopropyl alcohol)

• OTC SPONGE: 0.7%/74%

Canadian Trade Name(s)

• N/A

Canadian Availability

• N/A

UK Trade Name(s)

• N/A

UK Availability

• N/A

Australian Trade Name(s)

• N/A

Australian Availability

• N/A

[Outline]

Dermatologic

Miscellaneous Topical Agents