section name header

Interacting Drugs

OBJECT DRUGS

PRECIPITANT DRUGS


Comment:

Combined oral contraceptives have been shown in several studies to substantially reduce lamotrigine plasma concentrations; reduced lamotrigine efficacy may occur. The most likely mechanism is enhanced lamotrigine glucuronidation caused by the estrogen component, ethinyl estradiol.


Class 3: Assess Risk & Take Action if Necessary