Adult Dosing

Xerosis

• Apply and rub thoroughly on the affected areas bid

Ichthyosis vulgaris

• Apply and rub thoroughly on the affected areas bid

Note:

• For topical use only

Pediatric Dosing

• Safety and effectiveness of ammonium lactate cream have not been established in pediatric patients <2 yrs
• Safety and effectiveness of ammonium lactate lotion have been established in infants and pediatric patients

Xerosis

• Apply and rub thoroughly on the affected areas bid

Ichthyosis vulgaris

• Apply and rub thoroughly on the affected areas bid

Note:

• For topical use only

[Outline]

• Adult Dosing
• Pediatric Dosing

• Treatment of xerosis and ichthyosis vulgaris, and temporary relief of itching associated with these conditions

• Hypersensitivity to any of the ingredients of the product

• N/A

Renal Dose Adjustment

• Renal impairment: Dose adjustments not defined

Hepatic Dose Adjustment

• Hepatic impairment: Dose adjustments not defined

See Supplemental Patient Information

• Patients should avoid or minimize exposure of natural/artificial sunlight to areas of the skin treated with the drug. If hypersensitivity occurs, discontinue drug promptly
• Patients should avoid application on skin with fissures, erosions or abrasions as it may cause stinging or burning
• May cause irritation when applied on the face; hence, caution is advised
• Use ammonium lactate as directed by the physician and for external use only

Supplemental Patient Information

• Instruct patients to avoid contact with the eyes, lips, or mucous membranes
• Advise patients to use protective clothing and avoid excessive sun exposure
• Inform patients to promptly discontinue the medication if the skin condition worsens with treatment

Pregnancy Category:B

Breastfeeding: The extent of excretion in breast milk is unknown. As many drugs are excreted in human milk, manufacturer advises caution.

• DERM: Rash, transient stinging, erythema, peeling, irritation, burning, itching, dry skin, pruritus, photosensitivity
• HYPERSENSITIVITY: Hypersensitivity reactions

• Humectant/keratolytic/emollient; exact mechanism of action is unknown, may influence hydration of the stratum corneum and reduction of corneocyte cohesion
• Systemic absorption is minimal
• Metabolism: Unknown
• Excretion: Unknown
• Half-life: Unknown

US Trade Name(s)

• Lac-Hydrin

US Availability

ammonium lactate (generic)

• CRE: 12%
• LOTN: 12%

Lac-Hydrin

• CRE: 12%
• LOTN: 12%

Canadian Trade Name(s)

• N/A

Canadian Availability

• N/A

UK Trade Name(s)

• N/A

UK Availability

• N/A

Australian Trade Name(s)

• Lanate

Australian Availability

Lanate

• CRE: 17.5%

[Outline]

Dermatologic

Dermatologic Topical Agents

Emollients

Pricing data from www.DrugStore.com in U.S.A.

• Ammonium Lactate 12 % LOTN [Bottle] (PERRIGO)
  400 % = $27.99
  1200 % = $65.97
• Lac-Hydrin 12 % LOTN [Bottle] (RANBAXY LABORATORIES)
  225 % = $53.91
  675 % = $135.9
• Lac-Hydrin 12 % LOTN [Bottle] (RANBAXY LABORATORIES)
  400 % = $72.99
  1200 % = $201.98
• Lac-Hydrin 12 % CREA [Tube] (RANBAXY LABORATORIES)
  140 % = $51.99
  280 % = $95.97
• Ammonium Lactate 12 % CREA [Tube] (PERRIGO PHARMACEUTICALS)
  385 % = $45.99
  1155 % = $119.98
• Ammonium Lactate 12 % CREA [Tube] (PERRIGO PHARMACEUTICALS)
  280 % = $34.47
  840 % = $97.67
• Lac-Hydrin 12 % CREA [Bottle] (RANBAXY LABORATORIES)
  385 % = $64.99
  1155 % = $175.98
• Ammonium Lactate 12 % CREA [Tube] (PERRIGO)
  140 % = $14.99
  280 % = $25.98

Warning: This pricing information is subject to change at the sole discretion of DS Pharmacy. For the most current and up-to-date pricing information, please visit drugstore.com.