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Use and Dosing

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Seasonal or perennial allergic rhinitis

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Seasonal or perennial allergic rhinitis (>12 yrs)


[Outline]

Indications

Contraindications

Black Box Warnings

Dosing Adjustment

Renal Dose Adjustment (Based on CrCl)

Hepatic Dose Adjustment

Warnings/Precautions

See Supplemental Patient Information

Cautions: Use cautiously in

Supplemental Patient Information

Pregnancy/Breast Feeding

Pregnancy Category:C

Breastfeeding: Prolong use or high dose of cetirizine may cause drowsiness and other effects in the infant or decrease the milk supply if used before lactation is well established or in combination with a sympathomimetic such as pseudoephedrine. The British Society for Allergy and Clinical Immunology recommends lower dose of cetirizine if an antihistamine is required during breastfeeding. Small amounts of pseudoephedrine in breastmilk are unlikely to harm the nursing infant, however may cause irritability occasionally. Acute decrease in milk production can occur with a single dose of pseudoephedrine and repeated doses may interfere with lactation. Therefore mothers of newborns whose lactation is not yet well established or having difficulties producing sufficient milk should not receive pseudoephedrine. This information is based upon LactMed database (available at http://toxnet.nlm.nih.gov/cgi-bin/sis/htmlgen?LACT last accessed 23 February 2011). As per manufacturer's data as both cetirizine and pseudoephedrine are excreted in milk, use of cetirizine/pseudoephedrine is not recommended in nursing mothers.

Adverse Reactions

Clinical Pharmacology

Cetirizine

Pseudoephedrine

Brands and Availability

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US Trade Name(s)

US Availability

cetirizine/pseudoephedrine (generic)

Zyrtec-D 12 Hour (cetirizine/pseudoephedrine)

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Canadian Trade Name(s)

Canadian Availability

Reactine Allergy & Sinus (cetirizine/pseudoephedrine)

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UK Trade Name(s)

UK Availability

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Australian Trade Name(s)

Australian Availability


[Outline]

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Classification

ENT

Upper Respiratory Combinations

Pulmonary

Upper Respiratory Combinations

Pricing

Pricing data from www.DrugStore.com in U.S.A.

Warning.gifWarning: This pricing information is subject to change at the sole discretion of DS Pharmacy. For the most current and up-to-date pricing information, please visit drugstore.com.

Pill