Adult Dosing

Prevention of dental caries

• GEL, PASTE, CREAM
• Apply thin ribbon to a toothbrush and brush thoroughly for 2 minutes qd, preferably at bedtime; expectorate after brushing

• RINSE
• 5-10 mL PO qd; swish for 1 minute without swallowing, then expectorate
• Use immediately after brushing or flossing teeth

Note:

• Do not eat, drink, or rinse mouth for 30 minutes after using sodium fluoride

Pediatric Dosing

• Safety and effectiveness in pediatric patients <6 yrs have not been established

Prevention of dental caries (Children >6 Yrs)

• GEL, PASTE, CREAM
• Apply thin ribbon to a toothbrush and brush thoroughly for 2 minutes qd, preferably at bedtime; expectorate after brushing

• RINSE
• 5-10 mL PO qd; swish for 1 minute without swallowing, then expectorate
• Use immediately after brushing or flossing teeth

Note:

• Do not eat, drink, or rinse mouth for 30 minutes after using sodium fluoride

[Outline]

• Adult Dosing
• Pediatric Dosing

• Aids in the prevention of dental caries

• Hypersensitivity to any of the ingredients of the product
• Pediatric patients <6 yrs

• N/A

Renal Dose Adjustment

• Renal impairment: Dose adjustments not defined; caution advised

Hepatic Dose Adjustment

• Hepatic impairment: Dose adjustments not defined

See Supplemental Patient Information

• Not intended for systemic treatment; do not swallow
• Continuous daily ingestion may result in varying degrees of dental fluorosis in young children <6 yrs of age, particularly if water fluoridation exceeds 0.6 ppm. Use with caution in pediatric patients to prevent repeated swallowing which could cause dental fluorosis
• Supervise use in children; avoid use in children unable to expectorate content
• Product may cause irritation if there is any gum diseases; withhold therapy if irritation occurs
• Do not use fluoride topical if fluoride level in drinking water is greater than 0.7 ppm
• Keep out of reach of infants and children
• Promptly seek medical attention or contact a Poison Control Center if more than used for rinsing is accidentally swallowed

Cautions: Use cautiously in

• Renal impairment
• Pediatric patients <12 yrs
• Mucositis
• Low-sodium diet
• Peptic ulcer disease
• Severe joint pain

Supplemental Patient Information

• Advise caregivers or guardians to supervise the use of sodium fluoride in pediatric patients (<12 yrs) to prevent repeated swallowing
• Advise patients not to eat, drink, or rinse mouth for 30 minutes after using this product

Pregnancy Category:B

Breastfeeding: Safety unknown. It is unknown whether fluoride is excreted in human milk. Manufacturer advises caution.

• CNS: Heachache
• GI: Nausea, vomiting, stomach pain, diarrhea
• ORAL: Local irritation, discoloration of teeth, dental fluorosis (if swallowed by pediatric patients), weakened tooth enamel, sialorrhea, mouth/gum irritation
• MISC: Allergic reaction

• Cariostatic agent; increases tooth resistance to acid dissolution and enhances penetration of the fluoride ion into tooth enamel promoting tooth remineralization and inhibiting development of caries
• Metabolism: Unknown
• Renally excreted
• Half-life: Unknown

US Trade Name(s)

• Phos-Flur Gel
• Phos-Flur Rinse
• PreviDent
• PreviDent 5000 Booster
• PreviDent 5000 Dry Mouth
• PreviDent 5000 Plus

US Availability

Phos-Flur Gel, PreviDent 5000 Booster, PreviDent 5000 Dry Mouth

• GEL: 1.1%

Phos-Flur Rinse

• SOLN: 0.044%

PreviDent

• GEL: 1.1%
• SOLN: 0.2%

PreviDent 5000 Plus

• CRE: 1.1%

Canadian Trade Name(s)

• N/A

Canadian Availability

• N/A

UK Trade Name(s)

• N/A

UK Availability

• N/A

Australian Trade Name(s)

• NeutraFluor 220 Daily Fluoride Rinse
• NeutraFluor 5000 Plus Toothpaste
• NeutraFluor 900 Weekly Fluoride Rinse

Australian Availability

NeutraFluor 220 Daily Fluoride Rinse

• SOLN: 0.05%

NeutraFluor 5000 Plus Toothpaste

• PASTE: 1.1%

NeutraFluor 900 Weekly Fluoride Rinse

• SOLN: 0.2%

[Outline]

Dental

Dental Caries Agents

Pricing data from www.DrugStore.com in U.S.A.

• PreviDent 5000 Plus 1.1 % CREA [Box] (COLGATE ORAL PHARMACEUTICALS)
  102 % = $29.99
  204 % = $48.98
• PreviDent 5000 Booster 1.1 % PSTE [Bottle] (COLGATE ORAL PHARMACEUTICALS)
  100 % = $22
  200 % = $33
• PreviDent 5000 Plus 1.1 % CREA [Tube] (COLGATE ORAL PHARMACEUTICALS)
  51 % = $22
  102 % = $32.46
• PreviDent 0.2 % SOLN [Bottle] (COLGATE ORAL PHARMACEUTICALS)
  473 % = $21.99
  946 % = $32.97
• PreviDent 5000 Booster 1.1 % PSTE [Bottle] (COLGATE ORAL PHARMACEUTICALS)
  100 % = $21.99
  200 % = $32.97
• Sodium Fluoride 1.1 (0.5 F) MG/ML SOLN [Bottle] (SANCILIO)
  50 ml = $16.99
  100 ml = $25.98
• PreviDent 5000 Dry Mouth 1.1 % PSTE [Bottle] (COLGATE ORAL PHARMACEUTICALS)
  100 % = $22
  200 % = $32.97
• Sodium Fluoride 2.2 (1 F) MG CHEW [Bottle] (CYPRESS PHARMACEUTICAL)
  120 mg = $18.99
  240 mg = $26.98
• Sodium Fluoride 0.55 (0.25 F) MG CHEW [Bottle] (CYPRESS PHARMACEUTICAL)
  120 mg = $15.99
  240 mg = $20.97
• Sodium Fluoride 1.1 (0.5 F) MG CHEW [Bottle] (CYPRESS PHARMACEUTICAL)
  100 mg = $14.99
  200 mg = $18.97
• PreviDent 1.1 % GEL [Tube] (COLGATE ORAL PHARMACEUTICALS)
  56 % = $21.99
  112 % = $32.97

Warning: This pricing information is subject to change at the sole discretion of DS Pharmacy. For the most current and up-to-date pricing information, please visit drugstore.com.