section name header

Pronunciation

po-lee-ETH-e-leen GLYE-kole

Classifications

Therapeutic Classification: laxatives

Pharmacologic Classification: osmotics

Indications

REMS


Action

  • Polyethylene glycol in solution acts as an osmotic agent, drawing water into the lumen of the GI tract.
Therapeutic effects:
  • Evacuation of the GI tract without water or electrolyte imbalance.

Pharmacokinetics

Absorption: Nonabsorbable.

Distribution: Unknown.

Metabolism/Excretion: Excreted in fecal contents.

Half-Life: Unknown.

Time/Action Profile

(bowel movement)

ROUTEONSETPEAKDURATION
POunknown1–3 daysunknown





Contraind./Precautions

Contraindicated in:

Use Cautiously in:

Adv. Reactions/Side Effects

Derm: urticaria

GI: abdominal bloating, cramping, flatulence, nausea

Interactions

Drug-drug:

Route/Dosage

Availability

(Generic available)

Assessment

Implementation

Patient/Family Teaching

Evaluation/Desired Outcomes

US Brand Names

Gavilax, GlycoLax, MiraLax

Canadian Brand Names

ClearLax, Comfilax, Emolax, Hydralax, Lax-a-Day, PegaLax, Relaxa, RestoraLax