section name header

Pronunciation

dye-peer-ID-a-mole

Classifications

Therapeutic Classification: antiplatelet agents, diagnostic agents (coronary vasodilators)

Pharmacologic Classification: platelet adhesion inhibitors

Indications

BEERS REMS

Action

Therapeutic Effects:

Pharmacokinetics

Absorption: Moderately absorbed (30–60%) after oral administration. IV administration results in complete bioavailability.

Distribution: Widely distributed to tissues.

Metabolism/Excretion: Metabolized by the liver; excreted in the bile.

Half-life: 10 hr.

Time/Action Profile

(PO = antiplatelet activity, IV = coronary vasodilation)

ROUTEONSETPEAKDURATION
POunknownunknownunknown
IVunknown6.5 min30 min

†From start of infusion.

Contraind./Precautions

Contraindicated in:

Use Cautiously in:

Adv. Reactions/Side Effects

CV: hypotension, arrhythmias, flushing.
IV only: MI.

GI: nausea, diarrhea, GI upset, vomiting.

Derm: rash.

Neuro: dizziness, headache, syncope.
IV only: transient cerebral ischemia, weakness.

Resp: IV only: bronchospasm.

Interactions

Drug-Drug:

Route/Dosage

see Calculator

Availability

(Generic available)

Assessment

Lab Test Considerations:

Implementation

Patient/Family Teaching

Evaluation/Desired Outcomes

US Brand Names

Persantine

Canadian Brand Names

Persantine