bacitracin

bas-i-TRAY-sin

Therapeutic Classification: anti-infectives

REMS

Inhibits bacterial cell wall synthesis by preventing transfer of mucopeptides into growing cell wall.

Therapeutic effects:

Spectrum:

Absorption: Poorly absorbed from mucous membranes.

Distribution: Poor penetration into CSF.

Metabolism/Excretion: 10–40% excreted in urine within 24 hr.

Half-Life: Unknown.

(blood levels)

ROUTE	ONSET	PEAK	DURATION
Topical	unknown	unknown	unknown

Contraindicated in:

Use Cautiously in:

Derm: rash

Drug-drug:

↑incidence of nephrotoxicity with other nephrotoxic drugs; avoid concurrent use.

(Generic available)

Apply small amount of ointment to affected area; may be covered with a sterile bandage.

Instruct patient to only for use on minor cuts or burns. Do not use on animal bites, puncture wounds, serious burns, or deep cuts.
Inform patient that topical form may cause contact dermatitis or pruritus.
Advise patient to use only as long as prescribed; prolonged use may cause overgrowth of resistant organisms.
Advise patient to notify health care professional if pregnancy is planned or suspected or if breastfeeding.

Bacitin