section name header

Pronunciation

te-tra-SYE-kleen

Classifications

Therapeutic Classification: anti-infectives

Pharmacologic Classification: tetracyclines

Indications

REMS

Action

Therapeutic Effects:

Spectrum:

Pharmacokinetics

Absorption: 60–80% absorbed after oral administration.

Distribution: Widely distributed, some CSF and good bone penetration; crosses the placenta and enters breast milk.

Metabolism/Excretion: Excreted mostly unchanged by the kidneys.

Half-life: 6–12 hr.

Time/Action Profile

(blood levels)

ROUTEONSETPEAKDURATION
PO1–2 hr2–4 hr6–12 hr

Contraind./Precautions

Contraindicated in:

Use Cautiously in:

Adv. Reactions/Side Effects

Derm: photosensitivity, rashes.

GI: diarrhea, nausea, vomiting, esophagitis, hepatotoxicity, pancreatitis.

Hemat: blood dyscrasias.

Neuro: dizziness, intracranial hypertension.
Misc: hypersensitivity reactions, superinfection.

Interactions

Drug-Drug:

Drug-Food:

Route/Dosage

Availability

(Generic available)

Assessment

Lab Test Considerations:

Implementation

Patient/Family Teaching

Evaluation/Desired Outcomes

US Brand Names

Sumycin