REMS
Absorption: Rapidly absorbed; bioavailability unknown.
Distribution: Well distributed to tissues.
Half-Life: 15 hr.
Contraindicated in:
Use Cautiously in:
CV: arrhythmias, chest pain, hypertension, hypotension, syncope
Derm: dry skin, rash, STEVENS-JOHNSON SYNDROME (SJS)
EENT: rhinitis, abnormal vision, amblyopia, epistaxis, pharyngitis
Endo: hyperglycemia
F and E: ↑thirst
GI: ↑liver enzymes, nausea, anorexia, diarrhea, gingivitis, mouth ulcers, vomiting
GU: abnormal ejaculation, albuminuria, urinary retention
Hemat: eosinophilia
MS: joint disorder, neck pain
Neuro: headache, aggression, amnesia, anxiety, ataxia, cataplexy, confusion, delusions, depression, dizziness, dyskinesia, hallucinations, hypertonia, insomnia, mania, paresthesia, SEIZURES, SUICIDAL IDEATION, tremor
Resp: dyspnea
Misc: HYPERSENSITIVITY REACTIONS (INCLUDING ANAPHYLAXIS AND ANGIOEDEMA), infection
Drug-drug:
Drug-Natural Products:
Hepatic Impairment
Lab Test Considerations: