section name header

Pronunciation

bez-loe-TOX-ue-mab

Classifications

Therapeutic Classification: antidiarrheals

Pharmacologic Classification: monoclonal antibodies

Indications

REMS


Action

  • Binds to Clostridioides difficile toxin B and neutralizes its effects.
Therapeutic effects:
  • Reduced CDI recurrence.

Pharmacokinetics

Absorption: IV administration results in complete bioavailability.

Distribution: Minimally distributed to tissues.

Metabolism/Excretion: Eliminated primarily through catabolism.

Half-Life: 19 days.

Time/Action Profile

(plasma concentrations)

ROUTEONSETPEAKDURATION
IVunknownunknownunknown





Contraind./Precautions

Contraindicated in:

Use Cautiously in:

Adv. Reactions/Side Effects

Interactions

Drug-drug:

Route/Dosage

Availability

Assessment

Implementation

IV Administration:

Patient/Family Teaching

Evaluation/Desired Outcomes

US Brand Names

Zinplava