REMS
Spectrum:
Absorption: 35% absorbed following oral administration (high-fat meal ↓ rate and extent of absorption); IV administration results in complete bioavailability.
Distribution: Extensively distributed to tissues.
Half-Life: 1516 hr.
Contraindicated in:
Use Cautiously in:
CV: hypertension
Derm: photosensitivity
GI: nausea, vomiting, ↑liver enzymes, CLOSTRIDIOIDES DIFFICILE-ASSOCIATED DIARRHEA (CDAD), constipation, diarrhea
GU: ↓fertility
Local: injection site reactions
Community-Acquired Bacterial Pneumonia
Acute Bacterial Skin and Skin Structure Infections
IV Administration: