Absorption: 90% absorbed following oral administration.
Distribution: Unknown.
Protein Binding: 96%.
Half-Life: Without enzyme-inducing antiepileptic drugs: 79 hr; with enzyme-inducing antiepileptic drugs: 47 hr.
Contraindicated in:
Use Cautiously in:
CV: chest pain, edema, hypertension, palpitations, syncope, tachycardia
Derm: alopecia, dry skin, rash, sweating
EENT: abnormal vision, ear pain, tinnitus
GI: abdominal pain, gingivitis, nausea, stomatitis
GU: dysmenorrhea, dysuria, metrorrhagia, urinary incontinence
MS: arthralgia, neck pain
Neuro: dizziness, drowsiness, nervousness, weakness, ataxia, cognitive impairment, confusion, difficulty concentrating, hallucinations, headache, mental depression, personality disorder, SUICIDAL THOUGHTS, tremors
Misc: allergic reactions, chills, lymphadenopathy
Drug-drug:
Drug-Natural Products:
Toxicity and Overdose: