section name header

Pronunciation

GAR-lik

Classifications

Therapeutic Classification: lipid-lowering agents

Indications

Complementary/Alternative Medicine: This monograph describes a natural or herbal product that is not subject to FDA guidelines for medicines. Patients and clinicians are advised to read package labels carefully to ensure safe and efficacious use.

REMS


Action

  • May have HMG-CoA inhibitor properties in lowering cholesterol, but less effectively than statin drugs; vasodilatory and antiplatelet properties.
Therapeutic effects:
  • Decreased cholesterol levels.
  • Decreased platelet aggregation.

Pharmacokinetics

Absorption: Garlic oil is well absorbed.

Distribution: Unknown.

Metabolism/Excretion: Kidney and lungs.

Half-Life: Unknown.

Time/Action Profile

ROUTEONSETPEAKDURATION
PO4–25 wkunknownunknown



Contraind./Precautions

Contraindicated in:

Use Cautiously in:

Adv. Reactions/Side Effects

CNS: dizziness

GI: bad breath, diarrhea, flatulence, Irritation of the mouth, esophagus, and stomach, nausea, vomiting

Derm: Contact dermatitis and other allergic reactions (asthma, rash, anaphylaxis [rare]), Diaphoresis

Hemat: Chronic use or excessive dose may lead to hemoglobin production and lysis of RBCs, platelet dysfunction, prolonged bleeding time

Misc: body odor

Interactions

Natural-Drug Products:

Natural-Natural Products:

Route/Dosage

Availability

Assessment

Implementation

Patient/Family Teaching

Evaluation/Desired Outcomes

US Brand Names

Alli sativa bulbus, Allium sativum