REMS
Mycobacterium tuberculosis
resistant to at least rifampin and isoniazid (in combination with ≥3 other drugs).Absorption: Absorption following oral administration is doubled by food.
Distribution: Unknown.
Protein Binding: >99.9%.
Half-Life: 5.5 mo.
Contraindicated in:
Use Cautiously in:
CV: chest pain, QT interval prolongation
Derm: rash
GI: nausea, anorexia, HEPATOTOXICITY
MS: arthralgia
Neuro: headache
Resp: hemoptysis
Drug-drug:
Lab Test Considerations: