section name header

Pronunciation

KAL-see-um KAR-bo-nate

Classifications

Therapeutic Classification: mineral and electrolyte replacements/supplements

Indications

REMS


Action

  • Essential for nervous, muscular, and skeletal systems.
  • Maintain cell membrane and capillary permeability.
  • Act as an activator in the transmission of nerve impulses and contraction of cardiac, skeletal, and smooth muscle.
  • Essential for bone formation and blood coagulation.
Therapeutic effects:
  • Replacement of calcium in deficiency states. Control of hyperphosphatemia in end-stage renal disease without promoting aluminum absorption.

Pharmacokinetics

Absorption: Absorption from the GI tract requires vitamin D.

Distribution: Readily enters extracellular fluid. Crosses the placenta and enters breast milk.

Metabolism/Excretion: Excreted mostly in the feces; 20% eliminated by the kidneys.

Half-Life: Unknown.

Time/Action Profile

(effects on serum calcium)

ROUTEONSETPEAKDURATION
POunknownunknownunknown
IVimmediateimmediate0.5–2 hr





Contraind./Precautions

Contraindicated in:

Use Cautiously in:

Adv. Reactions/Side Effects

CV: arrhythmias, bradycardia

GI: constipation, nausea, vomiting

GU: calculi, hypercalciuria

Neuro: headache, tingling

Interactions

Drug-drug:

Route/Dosage

Availability

Assessment

Lab Test Considerations:

Toxicity and Overdose:

Implementation

Patient/Family Teaching

Evaluation/Desired Outcomes

US Brand Names

Alka-Mints, Amitone, BioCal, Calcarb, Calci-Chew, Calciday, Calcilac, Calci-Mix, Cal-Plus, Caltrate, Chooz, Dicarbosil, Equilet, Gencalc, Liqui-Cal, Liquid Cal-600, Maalox Antacid Caplets, Mallamint, Nephro-Calci, Os-Cal, Oysco, Oyst-Cal, Oystercal, Rolaids Calcium Rich, Surpass, Surpass Extra Strength, Titralac, Tums, Tums E-X

Canadian Brand Names

Apo-Cal, Calcite, Calglycine, Calsan, Mylanta Lozenges, Nu-Cal