section name header

Pronunciation

a-bal-oh-PAR-a-tide

Classifications

Therapeutic Classification: hormones

Pharmacologic Classification: parathyroid hormones

Indications

REMS


Action

  • Regulates calcium and phosphate metabolism in bone and kidney by binding to parathyroid hormone (PTH) receptors; stimulates osteoblastic activity.
Therapeutic effects:
  • Reduction in risk of vertebral and nonvertebral fractures in postmenopausal women and men.

Pharmacokinetics

Absorption: 36% absorbed after SUBQ administration.

Distribution: Widely distributed to tissues.

Metabolism/Excretion: Metabolized by the liver into peptide fragments which are renally excreted.

Half-Life: 1.7 hr.

Time/Action Profile

(serum concentrations)

ROUTEONSETPEAKDURATION
SUBQunknown0.51 hrunknown





Contraind./Precautions

Contraindicated in:

Use Cautiously in:

Adv. Reactions/Side Effects

Interactions

Drug-drug:

Route/Dosage

Availability

Assessment

Lab Test Considerations:

Implementation

Patient/Family Teaching

Evaluation/Desired Outcomes

US Brand Names

Tymlos