section name header

Pronunciation

ras-BYOOR-i-case

Classifications

Therapeutic Classification: antigout agents, antihyperuricemics

Pharmacologic Classification: enzymes

Indications

REMS

Action

Therapeutic Effects:

Pharmacokinetics

Absorption: IV administration results in complete bioavailability.

Distribution: Well distributed to tissues.

Metabolism/Excretion: Unknown.

Half-life: 18 hr.

Time/Action Profile

( in uric acid)

ROUTEONSETPEAKDURATION
IVrapidunknown4–24 hr

Contraind./Precautions

Contraindicated in:

Use Cautiously in:

Adv. Reactions/Side Effects

Derm: rash.

GI: abdominal pain, constipation, diarrhea, mucositis, nausea, vomiting.

Hemat: HEMOLYSIS, METHEMOGLOBINEMIA, neutropenia.

Neuro: headache.

Resp: respiratory distress.
Misc: fever, (INCLUDING ANAPHYLAXIS)HYPERSENSITIVITY REACTIONS , sepsis.

Interactions

Drug-Drug:

Route/Dosage

see Calculator

Availability

Assessment

Lab Test Considerations:

Implementation

Patient/Family Teaching

Evaluation/Desired Outcomes

US Brand Names

Elitek

Canadian Brand Names

Fasturtec