Therapeutic Classification: antiplatelet agents, antipyretics, nonopioid analgesics
Pharmacologic Classification: salicylates
Unlabeled Uses:
Absorption: Well absorbed from the upper small intestine; absorption from enteric-coated preparations may be unreliable; rectal absorption is slow and variable.
Distribution: Rapidly and widely distributed; crosses the placenta and enters breast milk.
Metabolism/Excretion: Extensively metabolized by the liver; inactive metabolites excreted by the kidneys. Amount excreted unchanged by the kidneys depends on urine pH; as pH increases, amount excreted unchanged increases from 23% up to 80%.
Half-life: 23 hr for low doses; up to 1530 hr with larger doses because of saturation of liver metabolism.
Contraindicated in:
Use Cautiously in:
Derm: DRUG REACTION WITH EOSINOPHILIA AND SYSTEMIC SYMPTOMS (DRESS), rash, urticaria.
EENT: tinnitus.
GI: dyspepsia, epigastric distress, nausea, abdominal pain, anorexia, GI BLEEDING, hepatotoxicity, vomiting.
Hemat: anemia, hemolysis.
Misc: (INCLUDING ANAPHYLAXIS AND LARYNGEAL EDEMA)HYPERSENSITIVITY REACTIONS .
Drug-Drug:
Drug-Natural Products:
Drug-Food:
Pain/Fever
Inflammation
Prevention of Transient Ischemic Attacks
Prevention of Myocardial Infarction/Antiplatelet Effects
Kawasaki Disease
(Generic available)
Acuprin, Aspergum, Aspir-Low, Aspirtab, Bayer Aspirin, Bayer Timed-Release Arthritic Pain Formula, Easprin, Ecotrin, 8-Hour Bayer Timed-Release, Empirin, Halfprin, Healthprin, Norwich Aspirin, Sloprin, St. Joseph Adult Chewable Aspirin, Therapy Bayer, Vazalore, ZORprin