section name header

Pronunciation

ma-la-THI-on

Classifications

Therapeutic Classification: pediculocides

Indications

REMS


Action

  • Acts as a cholinesterase inhibitor, causing death of lice and their eggs.
Therapeutic effects:
  • Eradication of head lice and their eggs.

Pharmacokinetics

Absorption: Minimal absorption (<10%) with topical application.

Distribution: Binds to hair shaft, which may protect against reinfestation.

Metabolism/Excretion: Metabolized to malaoxon, and excreted.

Half-Life: 8 hours.

Time/Action Profile

(pediculicidal effect)

ROUTEONSETPEAKDURATION
Topical6 hr12 hrpersists after application



Due to binding to hair shaft.



Contraind./Precautions

Contraindicated in:

Use Cautiously in:

Adv. Reactions/Side Effects

Derm: burns, scalp irritation

EENT: ocular irritation (with accidental eye exposure)

Interactions

Drug-drug:

Route/Dosage

Availability

(Generic available)

Assessment

Implementation

Patient/Family Teaching

Evaluation/Desired Outcomes

US Brand Names

Ovide

Pronunciation

Classifications

Indications

Action

Pharmacokinetics

Time/Action Profile

Contraind./Precautions

Adv. Reactions/Side Effects

Interactions

Route/Dosage

Availability

Assessment

Implementation

Patient/Family Teaching

Evaluation/Desired Outcomes

US Brand Names