section name header

Pronunciation

nye-STAT-in

Classifications

Therapeutic Classification: antifungals

Indications

REMS


Oral suspension

Oral tablet

Action

  • Binds to fungal cell membrane, allowing leakage of cellular contents.
Therapeutic effects:
  • Fungistatic or fungicidal action.

Spectrum:

Pharmacokinetics

Absorption: Poorly absorbed; action is primarily local.

Distribution: Unknown.

Metabolism/Excretion: Excreted unchanged in the feces after oral administration.

Half-Life: Unknown.

Time/Action Profile

(antifungal effects)

ROUTEONSETPEAKDURATION
PO24–72 hrunknownunknown





Contraind./Precautions

Contraindicated in:

Use Cautiously in:

Adv. Reactions/Side Effects

Derm: contact dermatitis, STEVENS-JOHNSON SYNDROME

GI: diarrhea, nausea, stomach pain (large doses), vomiting

Interactions

Drug-drug:

Route/Dosage

Oropharyngeal Candidiasis

Gastrointestinal Candidiasis

Availability

(Generic available)

Assessment

Implementation

Patient/Family Teaching

Evaluation/Desired Outcomes

US Brand Names

Mycostatin