May ↓ the effectiveness of esketamine; administer oxymetazoline ≥1 hr before esketamine.
May ↓ the effectiveness of zavegepant; avoid concurrent use. If concurrent use unavoidable, administer oxymetazoline ≥1 hr after zavegepant.
Route/Dosage⬆⬇
(Adults and Children ≥6 yr): 2–3 sprays into each nostril every 12 hr (not to exceed 2 doses/24 hr). Not to exceed duration of 3 days.
Availability⬆⬇
Nasal spray: 0.05% OTC
Assessment⬆⬇
Assess for treatment effectiveness on nasal and sinus congestion. If rebound congestion occurs, discontinue oxymetazoline.
Implementation⬆⬇
Squeeze bottle quickly, spraying into nostril. Do not tilt head backward. Wipe nozzle clean after use.
Patient/Family Teaching⬆⬇
Explain purpose and side effects of medication to patient. Advise patient to read Patient Information before starting therapy.
Advise patient not to use >3 days. If used longer than directed, oxymetazoline may cause rebound congestion and physical dependence. Notify health care professional if nasal symptoms continue or worsen or if dependence suspected.
Inform patients with ↑ BP, other cardiovascular disease, diabetes, thyroid disease, glaucoma, or benign prostatic hyperplasia to consult health care professional before using oxymetazoline.
Advise patient to not share container to prevent spread of infection.
Advise patient to notify health care professional of all Rx or OTC medications, vitamins, or herbal products being taken and to consult health care professional before taking other medications.
Rep: Advise patient to notify health care professional if pregnancy is planned or suspected, or if breastfeeding.
Evaluation/Desired Outcomes⬆⬇
Reduction of nasal congestion and sinus congestion/pressure.