section name header

Pronunciation

grayp seed EX-trakt

Classifications

Therapeutic Classification: cardioprotective agents

Indications

Complementary/Alternative Medicine: This monograph describes a natural or herbal product that is not subject to FDA guidelines for medicines. Patients and clinicians are advised to read package labels carefully to ensure safe and efficacious use.

REMS


Action

  • Grape flavonoids have a wide range of effects including antioxidant, vasodilatory, antiplatelet, decreased superoxide production, free-radical removal, and inhibition of collagenase.
Therapeutic effects:
  • Reduced risk of coronary disease.
  • Decreased skin and vasculature breakdown.

Pharmacokinetics

Absorption: Unknown.

Distribution: Unknown.

Metabolism/Excretion: Unknown.

Half-Life: Unknown.

Time/Action Profile

ONSETPEAKDURATION
POunknownunknownunknown

Contraind./Precautions

Contraindicated in:

Use Cautiously in:

Adv. Reactions/Side Effects

CV: hypertension

Derm: dry skin

EENT: cough, sore throat

GI: diarrhea, nausea

Hemat: risk of bleeding

Neuro: dizziness, headache

Interactions

Natural-Drug Products:

Natural-Natural Products:

Route/Dosage

Availability

Assessment

Lab Test Considerations:

Implementation

Patient/Family Teaching

Evaluation/Desired Outcomes

US Brand Names

Vitis vinifera, Vitis coignetiae, Oligomeric Proanthocyanidins (OPCs)