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Drug Name

mitapivat (Rx)

Pronunciation: (MYE-ta-PIV-at)

Trade Name(s): Pyrukynd

Func. class.: Antianemic agent

Uses

Hemolytic anemia in patients with pyruvate kinase (PK) deficiency

Dosage and Routes

Adults: PO 5 mg bid, then increase dose to 20 mg bid and then 50 mg bid q4wk if hemoglobin (Hb) is below normal or patient has required a transfusion within the last 8 wk. Maintain current dose if Hb is within normal and patient has not required a transfusion within the last 8 wk

Available forms: Tablet 5, 20, 50