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List of Diseases and Injuries

Estrogen, and other hormones and factors receptor status (Z17)

Z17Estrogen, and other hormones and factors receptor status


Use one code, as available, for each receptor: Z17.0, Z17.1, Z17.2-, Z17.3-


Code First: malignant neoplasm, such as:
› malignant neoplasm of breast (C50.-)
› malignant neoplasm of ovary (C56.-)

Z17.0Estrogen receptor positive status [ER+]

Z17.1Estrogen receptor negative status [ER-]

Z17.2Progesterone receptor status

Z17.21Progesterone receptor positive status
› PR+

Z17.22Progesterone receptor negative status
› PR-

Z17.3Human epidermal growth factor 2 receptor

Z17.31Human epidermal growth factor receptor 2 positive status
› HER2+

Z17.32Human epidermal growth factor receptor 2 negative status
› HER2-

Z17.4Combined receptor status


Assign a code from subcategory Z17.4- when only a combined receptor status is documented

Z17.41Hormone receptor positive
› HR+

Z17.410Hormone receptor positive with human epidermal growth factor receptor 2 positive status
› HR+ with HER2+

Z17.411Hormone receptor positive with human epidermal growth factor receptor 2 negative status
› HR+ with HER2-

Z17.42Hormone receptor negative
› HR-

Z17.420Hormone receptor negative with human epidermal growth factor receptor 2 positive status
› HR- with HER2+

Z17.421Hormone receptor negative with human epidermal growth factor receptor 2 negative status
› HR- with HER2-
› TNBC
› Triple negative breast cancer