Glucocorticoid and Mineralocorticoid Activity

Glucocorticoid and Mineralocorticoid Activity

Steroid	Glucocorticoid potency	Glucocorticoid equivalent dose	Mineralocorticoid potency	Mineralocorticoid equivalent dose
Cortisol/hydrocortisone	1	10 mg^a	0.0125	10 mg
Prednisone/prednisolone	4	2.5 mg	0.01	12.5 mg
Methylprednisolone	5	2 mg	0.003	40 mg^b
Dexamethasone	25	0.4 mg	0	NA^b
Fludrocortisone	10	1 mg^c	1.6	0.08 mg
Aldosterone	0	NA	1	0.125 mg^a

NA, not applicable.

^aAverage daily production in healthy adult subjects.

^bNot used for mineralocorticoid replacement therapy.

^cNot used for glucocorticoid replacement therapy.