Stop transfusion, check label on blood bag with patient wristband, and frequently monitor patient’s vital signs.

Send remaining donor blood and fresh patient sample to the blood bank for analysis.

Send patient sample to laboratory for CBC, LDH, and DIC screen.

Treat hypotension with fluids and/or vasopressors as necessary.

Consider use of corticosteroids.

Consider measures to preserve renal function and maintain brisk urine output (intravenous fluid, furosemide).

Monitor patient for DIC.