| Blood pressure | ≥140 mm Hg systolic or ≥90 mm Hg diastolic on two occasions at least 4 h apart after 20 wk of gestation in a woman with a previously normal blood pressure |
| ≥160 mm Hg systolic or ≥110 mm Hg diastolic, hypertension can be confirmed within a short interval (minutes) to facilitate timely antihypertensive therapy | |
| and | |
| Proteinuria | ≥300 mg per 24-h urine collection (or this amount extrapolated from a timed collection) |
| or | |
| Protein-creatinine ratio ≥0.3 (each measured by mg/dL) | |
| Dipstick reading of 1+ (used only if other quantitative methods are not available) | |
| Or in the absence of proteinuria, new-onset hypertension with the new onset of any of the following: | |
| Thrombocytopenia | Platelet count <100 000/μL |
| Renal insufficiency | Serum creatinine concentrations >1.1 mg/dL or a doubling of the serum creatinine concentration in the absence of other renal disease |
| Impaired liver function | Elevated blood concentrations of liver transaminases to twice normal concentration |
| Pulmonary edema | |
| Cerebral or visual symptoms | New-onset headache unresponsive to medication and not accounted for by alternative diagnoses or visual symptoms |
| Severe Features | |
| Blood pressure | SBP >160 mm Hg or DBP ≥110 mm Hg on two or more occasions at least 4 h apart (unless antihypertensive therapy is initiated before this time) |
| Thrombocytopenia | Platelet count <100 000/μL |
| Impaired liver function | Elevated blood concentrations of liver enzymes to twice the upper limit of normal or severe, persistent RUQ or epigastric pain unresponsive to medications that is not accounted for by alternative diagnoses |
| Renal insufficiency | Serum creatinine concentrations >1.1 mg/dL or a doubling of the serum creatinine concentration in the absence of other renal disease |
| Pulmonary edema | |
| Cerebral or visual disturbances | New-onset headache unresponsive to medication and not accounted for by alternative diagnoses or visual symptoms |
DBP, diastolic blood pressure; SBP, systolic blood pressure; RUQ, right upper quadrant.