Pseudo-addiction, as the name implies, is a mistaken diagnosis of addictive disease. The term was first used and the behaviors described in a case report by Weissman and Haddox (1989). When a patient’s pain is not well controlled, the patient may begin to manifest symptoms suggestive of addictive disease. In an effort to obtain adequate pain relief, the patient may respond with demanding behavior, escalating demands for more or different medications, repeated requests for opioids on time or before the prescribed interval between doses has elapsed, and frequent visits to the emergency department. As an example, patients who receive opioid doses that are too low or at intervals greater than the opioid’s duration of action may understandably try to manipulate the staff into giving them more analgesic. Pain relief typically eliminates these behaviors and is often accomplished by increasing opioid doses, decreasing intervals between doses, or providing an extra prescription in case it is needed.