The incidence of addiction as a result of taking an opioid for therapeutic reasons, such as postoperative pain management, is thought to be quite rare (Jackson, 2009). Research on long-term opioid use is limited (Pasero, Quinn, Portenoy, McCaffery, & Rizos, 2011). An evidence-based review of all available studies on the development of addiction and aberrant drug-related behaviors in patients with persistent noncancer pain being treated with opioids calculated the percentage of abuse and/or addiction following opioid therapy to be 0.19% (Fishbain, Cole, Lewis, Rosomoff, & Rosomoff, 2008). These data are reassuring, suggesting that patients with no past or present history of abuse or addiction usually remain responsible medication users over time. Similarly, a registry study of patients who were treated with modified-release oxycodone and followed for up to 3 years after participating in a clinical trial also showed a very low occurrence of problematic drug-related behavior- of the 227 patients studied, there were just six cases of misuse and no cases of new addiction (Portenoy et al., 2007).