Disseminated intravascular coagulation (DIC) results from an imbalance between coagulation factors, platelet production, and the consumption of coagulation factors and platelets. DIC occurs in patients who have trauma, sepsis, malignancy, and rarely, complicated obstetric cases (Levi, Toh, Thachil, & Watson, 2009). Treatment involves removing or treating the cause (trauma, sepsis) and transfusion if platelets <10,000 microL and patient is bleeding or requiring an invasive procedure, use of anticoagulants, and in patients with purpura fulminans (also known as purpura gangrenosa) administration of protein C concentrate (Gando et al., 2008; Levi, Toh, Thachil, & Watson, 2009). Lab anomalies in the patient with DIC are displayed in Table 17-7(Gando et al., 2008; Levi, Toh, Thachil, & Watson, 2009).