Most centers rely on standard manual compression as the gold standard since closure devices may offer a false sense of security because they are not associated with decreased access site complications and the cost is increased significantly (Kyunghee et al., 2013). Apply two or three fingers in a continuous downward pressure above the puncture site. Using enough pressure to stop the bleeding while maintaining a diminished distal pulse, hold for approximately 20 minutes or follow your own hospital protocol (Shoulders-Odom, 2008).