Pain is a complex phenomenon involving multiple underlying mechanisms. These characteristics mandate the use of more than one analgesic, sometimes provided by more than one route of administration, to manage immediate and ongoing postoperative pain. Guidelines recommend the use of multimodal analgesia as a means of reducing postoperative opioid doses and preventing clinically significant opioid-induced adverse effects (American Society of Anesthesiologists [ASA], 2012). For example, numerous studies have demonstrated that the combination of nonopioids (e.g., acetaminophen and nonsteroidal anti-inflammatory drugs [NSAIDs]) with other analgesics (e.g., opioids and local anesthetics) can produce better analgesia with fewer adverse effects than any single analgesic administered alone (American Pain Society, 2016; ASA, 2012; Derry, Derry, & Moore, 2013; Gritsenko, Khelemsky, Kaye, Vadivelu, & Urman, 2014; Jarzyna et al., 2011; Joshi, Schug, & Kehlet, 2014; Pasero & Stannard, 2012; Maund et al., 2011; Santosa, Ulm, Jennings, & Wan, 2014). A strong nonopioid foundation before opioid administration is strongly encouraged (Jarzyna et al., 2011; Pasero & Stannard, 2012; The Joint Commission, 2012). Nonpharmacologic approaches such as proper positioning and the application of heat or cold should be added to complement the pharmacologic treatment plan (The Joint Commission, 2012).