A. Postural (Action) Tremor
- Essential Tremor (most common)
- Alcoholic Tremor
- Orthostatic Tremor
- Tremor with Peripheral Neuropathy: Hereditary or Acquired
- Post-Traumatic Tremor
- Parkinson's Disease
- Wilson's Disease
- Hyperadrenergic Conditions
- Hyperthyroidism / Thyrotoxicosis
- Pheochromocytoma
- Dystonia
- Action tremor in affected body part without affecting other parts
- May be focal, generalized, or task-specific
- Physiologic Tremor (rapid rate, 8-12 Hz; Hz=Herz=cycles per second)
B. Rest Tremor
- Basal Ganglia Lesion Tremors are often at rest
- Parkinson's Disease (slow rate, 4-6 Hz)
- Wilson's Disease: wing-beating tremor; proximal tremor at shoulders
C. Intention Tremor
- Coarse terminal tremor occurs as limb approaches a target
- Cerebellar Tremor (3-5 Hz): often accompanied by ataxic gait, nystagmus, slurred speech
- Multiple Sclerosis (cerebellar lesions)
- Rubral Tremor
D. Task Specific Tremor
- Primary writing tremor
- Vocal tremor
E. Cortical Tremor
- Also called Rhythmic Cortical Myoclonus
- Irregular high-frequency (7-14 Hz) postural and kinetic tremor
- Cortical myoclonus
- Giant somatosensory cortical-evoked potentials
- Enhanced long-loop somatosensory (C-) reflexes
F. Drug Inudced Tremors
- Acetylcholine, Anticholinesterases
- Neuroleptics, Lithium
- Levodopa
- Tricyclic Antidepressants
- Caffeine
- Cigarettes (nicotine)
- Amphetamines
- Adrenaline (including Primatene®)
- ß-Adrenergic Agonists
- Theophylline
- Glucocorticoids (prednisone, hydrocortisone, others)
- Fluorouracil (5-FU)
- Amiodarone
- Alcohol
References
- Pahwa R and Lyons KE. 2003. Am J Med. 115(2):134
