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Info


A. Mnemonic: "Terrible T's"

  1. Thymoma
  2. Teratoma (Germ Cell Tumors)
  3. Thyroid Carcinoma
  4. "Terrible" Lymphoma

B. Thymoma [2]

  1. Age 30-50 years; Male = Female
  2. Asymptomatic in ~70%
  3. Local discomfort due to mass effect
  4. Associated with myasthenia gravis, anemia

C. Germ Cell Tumors

  1. Benign teratomas
  2. Malignant Germ Cell Tumor
    1. Usually in young men
    2. Typically with symptoms
    3. Seminoma
    4. Non-seminomatous germ-cell tumors
    5. Various tumor markers may be elevated

D. Thyroid Cancer

  1. Age <20, >60
  2. Male > Female
  3. Radiation exposure history
  4. Papillary > Follicular > Medullary types

E. Lymphoma

  1. Non-Hodgkin's Lymphoma (NHL)
    1. Diffuse Large B cell lymphoma
    2. Primary mediastinal large B-cell lymphoma
    3. Precursor T lymphoblastic lymphoma
  2. Hodgkin's Lymphoma
    1. Male = Female
    2. Usually nodular sclerosis type

References

  1. Shipp MA, Aquino SL, Harris NL. 2005. NEJM. 352(16):1697 (Case Record) abstract
  2. Wright CD, Fidias P, Choi NC, et al. 2007. NEJM. 356(21):2185 (Case Record) abstract