Potassium | |
unit | mmol/L mEq/L |
Base excess | |
unit | mmol/L mEq/L |
Platelet count (X 10^9/L) | |
C- Reactive Protein | |
unit | mg/dL mg/L |
The Rotterdam Score predicts death rate based upon 4 items in children with Meningococcal Septic Shock, in Children.
This score was developed retrospectively from clinical and laboratory characteristics of 75 children with meningococcal sepsis. The median age of these patients was 3.2 years and ranged from 3 weeks to 17.9 years.
In this series, 21% of these patients died and 17% of survivors had serious sequelae.
Using laboratory features found to be independently associated with mortality, this scoring system has a 71% predictive value for death, 90% predictive value for survival with outcome being predicted correctly for 86% of patients.
Laboratory Test |
Mean value Survivor |
Mean value Nonsurvivor |
Potassium |
3.4 mmol or mEq/L |
4.1 mmol or mEq/L |
Base excess |
-6.2 mmol or mEq/L |
-11.4 mmol or mEq/L |
Platelet count |
110x10 3 /mm 3 (x10 9 /L) |
63x10 3 /mm 3 (x10 9 /L) |
C-Reactive protein |
13.5 mg/dL (135 mg/L) |
8 mg/dL (80 mg/L) |
The Rotterdam Score (RS) is calculated by the following:
RS = 1.01 + (1.21 x Potassium) - (0.29 x Base Excess) - (0.024 x Platelets) - (3.75 x log serum CRP in units mg/L)
Predicted Death Rate = e (RS) /(1+e (RS) )
Reference:
Kornelisse RF et al. Meningococcal septic shock in children : clinical and laboratory features, outcome, and development of a prognostic score. Clin Infect Dis 1997;25:640-6