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1. Which of the following is not effective in post-exposure treatment of allergic rhinitis [1] ?

   A. Nasally inhaled glucocorticoids
   B. Nedocromil and Sodium Cromoglycolate
   C. H1-Blocking Antihistamines
   D. Weak alpha-adrenergic agonists (eg. pseudoephedrine, phenylpropanolamine)

2. Which of the following has been associated with prolongation of the QT interval [2]?

   A. Pseudoephedrine
   B. Diphenhydramine
   C. Acravistine
   D. Hismanal
   E. Brompheniramine

3. The reaction of some patients to radiocontrast dye is an example of [3]:

   A. Anaphylactoid Reaction
   B. Type 1 Hypersensitivity (IgE Mediated)
   C. Delayed Type Hypersensitivity (Type IV)
   D. Immune Complex Mediated Hypersensitivity (Type III)
   E. Abnormal Basophil Stimulation

4. Which of the following is NOT associated with Megaloblastic Anemia [4] ?

   A. Vitamin B12 Deficiency
   B. Folic Acid Deficiency
   C. Zidovudine (AZT) Therapy
   D. Trimethoprim Therapy
   E. Phenytoin (Dilantin) Therapy

5. Which of the following conditions does NOT mimic lymphoma on lymph node biopsy [5] ?

   A. Cat Scratch Disease
   B. Rheumatoid Arthritis
   C. Systemic Lupus Erythematosus
   D. Histiocytosis X (Langerhan's Cell)
   E. Syphilis

6. Which of the following are not associated food reactions [6] ?

   A. "Chinese Restaurant Syndrome" and Monosodium Glutamate (MSG) reaction
   B. Asthma and Sulfites
   C. Diarrhea and Lactose Intolerance
   D. Protein losing enteropathy and Red Meats
   E. Urticaria and Food Dyes

7. Hyperacute tissue graft rejection is caused by [7]:

   A. Host cytotoxic T lymphocytes infiltrating graft tissue
   B. Host antibodies against tissue graft present at time of transplant
   C. Host B lymphocytes and neutrophils infiltrating tissue graft
   D. Host helper T lymphocytes producing cytokines in graft
   E. Neutrophil and macrophage mediated graft destruction

8. Confirmation of the diagnosis of occupational asthma requires [8]:

   A. Methacholine induced bronchospasm
   B. Irritating agent induces bronchospasm
   C. Positive skin reaction to putative irritating agent
   D. Pre-existing asthma in the patient
   E. A forced expiratory volume (1 second; FEV1) of <60% of predicted value

9. A 22 year old man presents to the emergency room with increasing stridor. His tongue appears to be swollen. He has several attacks per year, and once required intubation to help him breath. The attacks last hours to days and apparently have no trigger. He thinks an uncle has similar attacks. The most likely diagnosis is [9]:

   A. Angioedema
   B. Urticaria with Asthma
   C. Intermittant Epiglotitis
   D. Tracheal Stenosis
   E. Systemic Vasculitis

10. In ischemic injury, the majority of tissue damage occurs during reperfusion. This is mainly to [10]:

    A. Arterial Dilation and Leukocyte Extravasation
    B. Venous Congestion with backup of blood
    C. Activation of proteases from killer lymphocytes
    D. Depletion of oxygen required for maintenance of intact mitochondria
    E. Calcium dependent activation of proteases leading to self-digestion

Answers

1. B
2. D
3. A
4. E
5. C
6. D
7. B
8. B
9. A
10. E