WHY is this medicine prescribed?
Furosemide injection is used to treat edema (excess fluid held in body tissues) caused by various medical problems in persons who cannot take medications by mouth or in emergency situations. Furosemide is in a class of medications called diuretics ('water pills'). It works by causing the kidneys to get rid of unneeded water and salt from the body.
HOW should this medicine be used?
Furosemide injection comes in an on-body infusor with a prefilled cartridge to inject subcutaneously (just under the skin) over about 5 hours once or twice a day. Furosemide injection also comes a solution (liquid) to be injected intramuscularly (into a muscle) or intravenously (into a vein) by a doctor or nurse in a medical office or hospital.
Use furosemide injection exactly as directed. Do not use more or less of it or use it more often than prescribed by your doctor.
You will be shown how to use the on-body injector by your doctor or nurse. You will be given instructions for use with the medicine. This will tell you how to inject it. Read it carefully. Ask your doctor or pharmacist if you have any questions on how to inject the medicine.
You will need to limit your activity and limit bending movements during the infusion using the on-body injector. You should notice an increased need to urinate starting about 1 hour after the injection begins. This may last up to 8 hours. Make sure that you have access to a bathroom for up to 8 hours after beginning the injection using the on-body injector. Call your doctor if you do not need to urinate a lot (at least 2 times) during the infusion.
Check the cartridge to be sure that the expiration date printed on the cartridge has not passed. Look closely at the liquid in the cartridge. The liquid should be clear to slightly yellow and should not be cloudy or discolored. Do not drop the on-body injector or cartridge or allow the injector to get wet. After you apply the on-body injector, do not shower, bathe, swim, or do activities that will make you sweat when you are wearing the on-body injector. Call your pharmacist if there are any problems with the package or the cartridge and do not inject the medication.
You can apply the on-body injector on the abdomen (stomach area) on either side of your navel in a flat, hairless area above the belt line and below the rib cage. Choose a different spot each time you apply the on-body injector. Do not apply the on-body injector in an area directly under a belt or waistband. Be sure that the skin in the area where you plan to apply the on-body injector is clean, dry, and healthy. Do not apply the on-body injector to skin that is red, irritated, or not intact. Also do not apply the on-body injector to skin that you have recently treated with creams, lotions, oils, or other skin products. Do not use the on-body infusor within 12 inches of mobile phones, tables, computers, or any other wireless devices (television remotes, Bluetooth keyboards or mouses).
Dispose of used on-body delivery systems in a puncture-resistant container. Talk to your doctor or pharmacist about how to dispose of the puncture-resistant container.
Ask your pharmacist or doctor for a copy of the manufacturer's information for the patient.
Are there OTHER USES for this medication?
This medication may be prescribed for other uses; ask your doctor or pharmacist for more information.
What SPECIAL PRECAUTIONS should I follow?
Before receiving furosemide injection,
What SPECIAL DIETARY instructions should I follow?
If your doctor prescribes a low-salt or low-sodium diet, or to eat or drink increased amounts of potassium-rich foods (e.g., bananas, prunes, raisins, and orange juice) in your diet, follow these instructions carefully.
What SIDE EFFECTS can this medicine cause?
Furosemide injection may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:
Some side effects can be serious. If you experience any of these symptoms, call your doctor immediately:
Furosemide injection may cause other side effects. Call your doctor if you have any unusual problems while receiving this medication.
If you experience a serious side effect, you or your doctor may send a report to the Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting program online (http://www.fda.gov/Safety/MedWatch) or by phone (1-800-332-1088).
What should I do in case of OVERDOSE?
In case of overdose, call the poison control helpline at 1-800-222-1222. Information is also available online at http://www.poisonhelp.org/help. If the victim has collapsed, had a seizure, has trouble breathing, or can't be awakened, immediately call emergency services at 911.
Symptoms of overdose may include:
What should I know about STORAGE and DISPOSAL of this medication?
Keep the on-body delivery system in the carton it came in, tightly closed, and out of reach of children. Store it at room temperature and protect from light and water. Do not refrigerate or freeze.
Keep all medication out of sight and reach of children as many containers are not child resistant. Always lock safety caps. Place the medication in a safe location - one that is up and away and out of their sight and reach. http://www.upandaway.org
Dispose of unneeded medications in a way so that pets, children, and other people cannot take them. Do not flush this medication down the toilet. Use a medicine take-back program. Talk to your pharmacist about take-back programs in your community. Visit the FDA's Safe Disposal of Medicines website (http://goo.gl/c4Rm4p) for more information.
What OTHER INFORMATION should I know?
Keep all appointments with your doctor and the laboratory. Your doctor may order certain lab tests to check your body's response to furosemide injection.
Keep a written list of all of the prescription and nonprescription (over-the-counter) medicines vitamins, minerals, and dietary supplements you are taking. Bring this list with you each time you visit a doctor or if you are admitted to the hospital. You should carry the list with you in case of emergencies.
This report on medications is for your information only, and is not considered individual patient advice. Because of the changing nature of drug information, please consult your physician or pharmacist about specific clinical use.
The American Society of Health-System Pharmacists, Inc. represents that the information provided hereunder was formulated with a reasonable standard of care, and in conformity with professional standards in the field. The American Society of Health-System Pharmacists, Inc. makes no representations or warranties, express or implied, including, but not limited to, any implied warranty of merchantability and/or fitness for a particular purpose, with respect to such information and specifically disclaims all such warranties. Users are advised that decisions regarding drug therapy are complex medical decisions requiring the independent, informed decision of an appropriate health care professional, and the information is provided for informational purposes only. The entire monograph for a drug should be reviewed for a thorough understanding of the drug's actions, uses and side effects. The American Society of Health-System Pharmacists, Inc. does not endorse or recommend the use of any drug. The information is not a substitute for medical care.
AHFS® Patient Medication Information™ Copyright, 2025. The American Society of Health-System Pharmacists®, 4500 East-West Highway, Suite 900, Bethesda, Maryland. All Rights Reserved. Duplication for commercial use must be authorized by ASHP.
Selected Revisions: December 15, 2025.