WHY is this medicine prescribed?
Efgartigimod alfa and hyaluronidase-qvfc injection is used to treat a certain form of myasthenia gravis (MG; a disorder of the nervous system that causes muscle weakness). Efgartigimod alfa and hyaluronidase-qvfc injection is also used to treat chronic inflammatory demyelinating polyneuropathy (CIDP; a disorder of the immune and nervous systems). Efgartigimod alfa-fcab is in a group of medications called monoclonal antibodies. It works by reducing a certain natural substance in the body that causes symptoms of myasthenia gravis and chronic inflammatory demyelinating polyneuropathy. Hyaluronidase-qvfc is an endoglycosidase. It helps to keep efgartigimod alfa in the body longer so that the medication will have a greater effect.
HOW should this medicine be used?
Efgartigimod alfa and hyaluronidase-qvfc injection comes as a solution (liquid) to be injected subcutaneously (just under the skin) into the abdomen (stomach) over 30 to 90 seconds by a healthcare provider. When efgartigimod alfa and hyaluronidase-qvfc injection is given to treat myasthenia gravis, is usually injected once a week for 4 weeks. This cycle may be repeated as recommended by your doctor, but no sooner than at least 50 days after your last weekly dose. When efgartigimod alfa and hyaluronidase-qvfc injection is given to treat chronic inflammatory demyelinating polyneuropathy, it is usually given once a week. The length of your treatment depends on how well your body responds to the medication and any side effects that you experience.
Efgartigimod alfa and hyaluronidase-qvfc injection may cause serious reactions, usually within 1 hour after your receive the injection. Your healthcare provider will watch you carefully while you are receiving efgartigimod alfa and hyaluronidase-qvfc injection and for at least 30 minutes after you receive the medication. If you experience any of the following symptoms, tell your doctor immediately: chest pain; feeling dizzy, lightheaded, or faint; rash; hives; swelling of the eyes, face, lips, tongue, or throat; hoarseness; difficulty breathing or swallowing; chills; shivering; or stomach or back pain.
Ask your pharmacist or doctor for a copy of the manufacturer's information for the patient.
Are there OTHER USES for this medication?
This medication may be prescribed for other uses; ask your doctor or pharmacist for more information.
What SPECIAL PRECAUTIONS should I follow?
Before receiving efgartigimod alfa and hyaluronidase-qvfc injection,
What SPECIAL DIETARY instructions should I follow?
Unless your doctor tells you otherwise, continue your normal diet.
What should I do IF I FORGET to take a dose?
If you miss an appointment to receive a dose of efgartigimod alfa and hyaluronidase-qvfc injection, call your doctor right away.
What SIDE EFFECTS can this medicine cause?
Efgartigimod alfa and hyaluronidase-qvfc injection may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:
Some side effects can be serious. If you experience any of these symptoms, call your doctor immediately:
Efgartigimod alfa and hyaluronidase-qvfc injection may cause other side effects. Call your doctor if you have any unusual problems while taking this medication.
If you experience a serious side effect, you or your doctor may send a report to the Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting program online (http://www.fda.gov/Safety/MedWatch) or by phone (1-800-332-1088).
What should I do in case of OVERDOSE?
In case of overdose, call the poison control helpline at 1-800-222-1222. Information is also available online at http://www.poisonhelp.org/help. If the victim has collapsed, had a seizure, has trouble breathing, or can't be awakened, immediately call emergency services at 911.
What OTHER INFORMATION should I know?
Keep all appointments with your doctor.
Keep a written list of all of the prescription and nonprescription (over-the-counter) medicines, vitamins, minerals, and dietary supplements you are taking. Bring this list with you each time you visit a doctor or if you are admitted to the hospital. You should carry the list with you in case of emergencies.
This report on medications is for your information only, and is not considered individual patient advice. Because of the changing nature of drug information, please consult your physician or pharmacist about specific clinical use.
The American Society of Health-System Pharmacists, Inc. represents that the information provided hereunder was formulated with a reasonable standard of care, and in conformity with professional standards in the field. The American Society of Health-System Pharmacists, Inc. makes no representations or warranties, express or implied, including, but not limited to, any implied warranty of merchantability and/or fitness for a particular purpose, with respect to such information and specifically disclaims all such warranties. Users are advised that decisions regarding drug therapy are complex medical decisions requiring the independent, informed decision of an appropriate health care professional, and the information is provided for informational purposes only. The entire monograph for a drug should be reviewed for a thorough understanding of the drug's actions, uses and side effects. The American Society of Health-System Pharmacists, Inc. does not endorse or recommend the use of any drug. The information is not a substitute for medical care.
AHFS® Patient Medication Information™ Copyright, 2025. The American Society of Health-System Pharmacists®, 4500 East-West Highway, Suite 900, Bethesda, Maryland. All Rights Reserved. Duplication for commercial use must be authorized by ASHP.
Selected Revisions: October 20, 2024.