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General Information

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Use

WHY is this medicine prescribed?

Betamethasone topical is used to treat the itching, redness, dryness, crusting, scaling, inflammation, and discomfort of various skin conditions, including psoriasis (a skin disease in which red, scaly patches form on some areas of the body) and eczema (a skin disease that causes the skin to be dry and itchy and to sometimes develop red, scaly rashes). Betamethasone is in a class of medications called corticosteroids. It works by activating natural substances in the skin to reduce swelling, redness, and itching.

HOW should this medicine be used?

Betamethasone comes in ointment, cream, lotion, gel, and aerosol (spray) in various strengths for use on the skin and as a foam to apply to the scalp. It is usually applied once or twice daily. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Use betamethasone exactly as directed. Do not use more or less of it or use it more often than prescribed by your doctor. Do not apply it to other areas of your body or use it to treat other skin conditions unless directed to do so by your doctor.

Your skin condition should improve during the first 2 weeks of your treatment. Call your doctor if your symptoms do not improve during this time.

To use betamethasone topical, apply a small amount of ointment, cream, solution, gel, or lotion to cover the affected area of skin with a thin even film and rub it in gently.

To use the foam on your scalp, part your hair, apply a small amount of the medicine on the affected area, and rub it in gently. You may wash your hair as usual but not right after applying the medicine.

Betamethasone foam may catch fire. Stay away from open fire, flames, and do not smoke while you are applying betamethasone foam, and for a short time afterward.

This medication is only for use on the skin. Do not let betamethasone topical get into your eyes or mouth and do not swallow it. Avoid use in the genital and rectal areas and in skin creases and armpits unless directed by your doctor.

If you are using betamethasone on a child's diaper area, do not use tight-fitting diapers or plastic pants. Such use may increase side effects.

Do not apply other skin preparations or products on the treated area without talking with your doctor.

Do not wrap or bandage the treated area unless your doctor tells you that you should. Such use may increase side effects.

Call your doctor if the treated area gets worse or if burning, swelling, redness, or oozing of pus develops.

Are there OTHER USES for this medication?

This medication may be prescribed for other uses; ask your doctor or pharmacist for more information.

Special

What SPECIAL PRECAUTIONS should I follow?

Before using betamethasone,

What should I do IF I FORGET to take a dose?

Apply the missed dose as soon as you remember it. However, if it is almost time for the next dose, skip the missed dose and continue your regular dosing schedule. Do not apply a double dose to make up for a missed one.

Side Effects

What SIDE EFFECTS can this medicine cause?

Betamethasone may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:

If you experience any of the following symptoms, call your doctor immediately:

Children who use betamethasone topical may have an increased risk of side effects including slowed growth and delayed weight gain. Talk to your child's doctor about the risks of applying this medication to your child's skin.

Betamethasone topical may cause other side effects. Call your doctor if you have any unusual problems while using this medication.

If you experience a serious side effect, you or your doctor may send a report to the Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting program online (http://www.fda.gov/Safety/MedWatch) or by phone (1-800-332-1088).

Overdose

What should I do in case of OVERDOSE?

If someone swallows betamethasone topical, call your local poison control center at 1-800-222-1222. If the victim has collapsed or is not breathing, call local emergency services at 911.

Storage

What should I know about STORAGE and DISPOSAL of this medication?

Keep this medication in the container it came in, tightly closed, and out of reach of children. Store it at room temperature and away from excess heat and moisture (not in the bathroom). Do not freeze it..

Keep all medication out of sight and reach of children as many containers are not child-resistant. Always lock safety caps. Place the medication in a safe location - one that is up and away and out of their sight and reach. http://www.upandaway.org

Dispose of unneeded medications in a way so that pets, children, and other people cannot take them. Do not flush this medication down the toilet. Use a medicine take-back program. Talk to your pharmacist about take-back programs in your community. Visit the FDA's Safe Disposal of Medicines website http://goo.gl/c4Rm4p for more information.

Miscellaneous

What OTHER INFORMATION should I know?

Keep all appointments with your doctor and the laboratory. Your doctor may order certain lab tests to check your body's response to betamethasone.

Do not let anyone else use your medication. Ask your pharmacist any questions you have about refilling your prescription.

Keep a written list of all of the prescription and nonprescription (over-the-counter) medicines, vitamins, minerals, and dietary supplements you are taking. Bring this list with you each time you visit a doctor or if you are admitted to the hospital. You should carry the list with you in case of emergencies.

¶ This branded product is no longer on the market. Generic alternatives may be available.

This report on medications is for your information only, and is not considered individual patient advice. Because of the changing nature of drug information, please consult your physician or pharmacist about specific clinical use.

The American Society of Health-System Pharmacists, Inc. represents that the information provided hereunder was formulated with a reasonable standard of care, and in conformity with professional standards in the field. The American Society of Health-System Pharmacists, Inc. makes no representations or warranties, express or implied, including, but not limited to, any implied warranty of merchantability and/or fitness for a particular purpose, with respect to such information and specifically disclaims all such warranties. Users are advised that decisions regarding drug therapy are complex medical decisions requiring the independent, informed decision of an appropriate health care professional, and the information is provided for informational purposes only. The entire monograph for a drug should be reviewed for a thorough understanding of the drug's actions, uses and side effects. The American Society of Health-System Pharmacists, Inc. does not endorse or recommend the use of any drug. The information is not a substitute for medical care.

AHFS® Patient Medication Information Copyright, 2025. The American Society of Health-System Pharmacists®, 4500 East-West Highway, Suite 900, Bethesda, Maryland. All Rights Reserved. Duplication for commercial use must be authorized by ASHP.

Selected Revisions: February 15, 2018.