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Table 4-9

Nitrate Preparations Commonly Used for Ischemic Heart Disease

PreparationDosageOnset (min)Duration
Sublingual nitroglycerin0.3–0.6 mg PRN2–510–30 min
Aerosol nitroglycerin0.4 mg PRN2–510–30 min
Oral isosorbide dinitrate5–40 mg tid30–604–6 h
Oral isosorbide mononitrate10–20 mg bid30–606–8 h
Oral isosorbide mononitrate SR30–120 mg daily30–6012–18 h
2% Nitroglycerin ointment0.5–2 in tid20–603–8 h
Transdermal nitroglycerin patches5–15 mg daily>6012 h
Intravenous nitroglycerin10–200 µg/min<2During infusion