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Question

What is the pathological staging using the seventh and eighth editions of the AJCC for the following case?

Fifty-seven-year-old female presents with palpable mass in the upper inner quadrant of the right breast. Physical examination revealed a 1.5-cm mobile breast mass. There were no skin changes or palpable LNs. Bilateral diagnostic mammogram was read as negative. Ultrasound demonstrated a 1.2-cm hypoechoic density with irregular margins. There were no internal vascularity or abnormal LNs. Ultrasound-guided core biopsy was consistent with invasive lobular carcinoma, nuclear grade 3. ER-(<1%)/PR-(<1%)/HER2/neu was not amplified. She underwent right partial mastectomy and sentinel LN biopsy. Pathology demonstrated a 1.4-cm tumor consistent with invasive lobular carcinoma nuclear grade 3 with negative margins. All three sentinel LNs were negative. Her oncotype score was 22.

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