Class I Recommendations for Use of an Early Invasive Strategy
| Recurrent angina/ischemia at rest or minimal exertion despite anti-ischemic therapy |
| Elevated cardiac TnT or TnI |
| New ST-segment depression |
| CHF symptoms, rales or worsening mitral regurgitation |
| Positive stress test |
| LVEF <0.40 |
| Hemodynamic instability or hypotension |
| Sustained ventricular tachycardia |
| PCI within previous 6 months, or prior CABG |
| Diabetes |
| Renal dysfunction |
| High-risk score |
Abbreviations: CABG, coronary artery bypass grafting; LVEF, left ventricular ejection fraction; PCI, percutaneous coronary intervention; TnI, troponin I; TnT, troponin T.
Source: Modified from JL Anderson et al: J Am Coll Cardiol 61:e179, 2013.