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Table 66-2

Staging of B-Cell CLL and Relation to Survival

StageClinical FeaturesMedian Survival, Years
RAI
0Lymphocytosis12
ILymphocytosis + adenopathy9
IILymphocytosis + splenomegaly7
IIIAnemia1-2
IVThrombocytopenia1-2
BINET
ANo anemia/thrombocytopenia, <3 involved sites>10
BNo anemia/thrombocytopenia, >3 involved sites5
CAnemia and/or thrombocytopenia2