Staging of B-Cell CLL and Relation to Survival
Stage | Clinical Features | Median Survival, Years |
---|---|---|
RAI | ||
0 | Lymphocytosis | 12 |
I | Lymphocytosis + adenopathy | 9 |
II | Lymphocytosis + splenomegaly | 7 |
III | Anemia | 1-2 |
IV | Thrombocytopenia | 1-2 |
BINET | ||
A | No anemia/thrombocytopenia, <3 involved sites | >10 |
B | No anemia/thrombocytopenia, >3 involved sites | 5 |
C | Anemia and/or thrombocytopenia | 2 |