Treatment Duration for Nocardiosis
| Disease | Duration |
|---|---|
| Pulmonary or systemic | |
| Intact host defenses | 6-12 months |
| Deficient host defenses | 12 monthsa |
| CNS disease | 12 monthsb |
| Cellulitis, lymphocutaneous syndrome | 2 months |
| Osteomyelitis, arthritis, laryngitis, sinusitis | 4 months |
| Actinomycetoma | 6-12 months after clinical cure |
| Keratitis | Topical: until apparent cure |
| Systemic: until 2-4 months after apparent cure |
aIn some pts with AIDS and CD4+ T lymphocyte counts of <200/µL or with chronic granulomatous disease, therapy for pulmonary or systemic disease must be continued indefinitely.
bIf all apparent CNS disease has been excised, the duration of therapy may be reduced to 6 months.