Classification of Urticaria and/or Angioedema
- IgE-dependent
- Specific antigen sensitivity (pollens, foods, drugs, fungi, molds, Hymenoptera venom, helminths)
- Physical: dermographism, cold, solar, pressure, cholinergic
- Autoimmune
- Bradykinin-mediated
- Hereditary angioedema: C1 inhibitor deficiency: null (type 1) and dysfunctional (type 2), mutated factor XII (type 3)
- Acquired angioedema: C1 inhibitor deficiency: anti-idiotype and anti-C1 inhibitor
- Angiotensin-converting enzyme inhibitors
- Complement-mediated
- Necrotizing vasculitis
- Serum sickness
- Reactions to blood products
- Nonimmunologic
- Direct mast cell-releasing agents (opiates, antibiotics, curare, D-tubocurarine, radiocontrast media)
- Agents that alter arachidonic acid metabolism (aspirin and nonsteroidal anti-inflammatory agents, azo dyes, and benzoates)
- Idiopathic
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