Approach to Chronic Disease is Based on Whether Glucocorticoid Therapy is Tolerated

Approach to Chronic Disease is Based on Whether Glucocorticoid Therapy is Tolerated - Flowchart

«Flowchart»

MANAGEMENT ALGORITHM OF CHRONIC DISEASE

MANAGEMENT ALGORITHM OF CHRONIC DISEASE ANAGEMENT LGORITHM OF HRONIC ISEASE

Alternative agents

Chronic disease

Glucocorticoids tolerated

Glucocorticoids not tolerated

Glucocorticoids not effective

Seek alternative agents

Continue therapy

Dose <10 mg/d

Yes

End

Methotrexate
Hydroxychloroquine
Azathioprine
Leflunomide
Mycophenolate
Minocycline

Try alternative agents

If effective, taper off glucocorticoids

If effective

If not effective, consider:

Multiple agents
Infliximab
Cyclophosphamide
Thalidomide

If not effective, consider:

Multiple agents
Infliximab
Cyclophosphamide
Thalidomide

Multiple agents
Infliximab
Cyclophosphamide
Thalidomide If not effective, consider