section name header

Table 40-3

Common Causes of Malabsorption

Maldigestion: Chronic pancreatitis, cystic fibrosis, pancreatic carcinoma
Bile salt deficiency: Cirrhosis, cholestasis, bacterial overgrowth (blind loop syndromes, intestinal diverticula, hypomotility disorders), impaired ileal reabsorption (resection, Crohn's disease), bile salt binders (cholestyramine, calcium carbonate, neomycin)
Inadequate absorptive surface: Massive intestinal resection, gastrocolic fistula, jejunoileal bypass
Lymphatic obstruction: Lymphoma, Whipple's disease, intestinal lymphangiectasia
Vascular disease: Constrictive pericarditis, right-sided heart failure, mesenteric arterial or venous insufficiency
Mucosal disease: Infection (esp. Giardia, Whipple's disease, tropical sprue), inflammatory diseases (esp. Crohn's disease), radiation enteritis, eosinophilic enteritis, ulcerative jejunitis, mastocytosis, tropical sprue, infiltrative disorders (amyloidosis, scleroderma, lymphoma, collagenous sprue, microscopic colitis), biochemical abnormalities (gluten-sensitive enteropathy, disaccharidase deficiency, hypogammaglobulinemia, abetalipoproteinemia, amino acid transport deficiencies), endocrine disorders (diabetes mellitus, hypoparathyroidism, adrenal insufficiency, hyperthyroidism, Zollinger-Ellison syndrome, carcinoid syndrome)