Hereditable (Autosomal Dominant)
| Gastrointestinal Polyposis Syndromes | ||||
|---|---|---|---|---|
| Syndrome | Distribution of Polyps | Histologic Type | Malignant Potential | Associated Lesions |
| Familial adenomatous polyposis | Large intestine | Adenoma | Common | None |
| Gardner's syndrome | Large and small intestines | Adenoma | Common | Osteomas, fibromas, lipomas, epidermoid cysts, ampullary cancers, congenital hypertrophy of retinal pigment epithelium |
| Turcot's syndrome | Large intestine | Adenoma | Common | Brain tumors |
| Nonpolyposis syndrome (Lynch syndrome) | Large intestine (often proximal) | Adenoma | Common | Endometrial and ovarian tumors |
| Peutz-Jeghers syndrome | Small and large intestines, stomach | Hamartoma | Rare | Mucocutaneous pigmentation; tumors of the ovary, breast, pancreas, endometrium |
| Juvenile polyposis | Large and small intestines, stomach | Hamartoma, rarely progressing to adenoma | Rare | Various congenital abnormalities |