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Table 115-1

Presentation with Symptomatic Cardiomyopathy

DilatedRestrictiveHypertrophic
Ejection fraction (normal >55%)Usually <30% when symptoms severe25-50%>60%
Left ventricular diastolic dimension (normal <55 mm)60 mm<60 mm (may be decreased)Often decreased
Left ventricular wall thicknessNormal or decreasedNormal or increasedMarkedly increased
Atrial sizeIncreasedIncreased; may be massiveIncreased
Valvular regurgitationRelated to annular dilationRelated to endocardial involvement; frequent mitral and tricuspid regurgitation, rarely severeRelated to valve-septum interaction; mitral regurgitation
Common first symptomsExertional intoleranceExertional intolerance, fluid retention earlyExertional intolerance; may have chest pain
Congestive symptomsaLeft before right, except right prominent in young adultsRight often dominatesLeft-sided congestion may develop late
ArrhythmiaVentricular tachyarrhythmia; conduction block in Chagas' disease, and some families. Atrial fibrillation.Ventricular uncommon except in sarcoidosis conduction block in sarcoidosis and amyloidosis. Atrial fibrillation.Ventricular tachyarrhythmias; atrial fibrillation

aLeft-sided symptoms of pulmonary congestion: dyspnea on exertion, orthopnea, paroxysmal nocturnal dyspnea. Right-sided symptoms of systemic versus congestion: discomfort on bending, hepatic and abdominal distention, peripheral edema.